Detection and localization of deep sources in magnetoencephalography: A review

Magnetoencephalography (MEG) is a noninvasive technique for exploring the spatiotemporal dynamics of brain networks with high temporal resolution as well good spatial capacities, thanks to relative insensitivity low skull conductivity. It tool choice both neuroscience research and clinical applications used routinely in epilepsy localizing sources epileptiform discharges. Still, capacity capturing deep sources, such hippocampus amygdala that are key players memory emotion, has been long topic debate. Thus, fine characterization structures up now reserved domain intracerebral stereo electroencephalography (SEEG), performed during presurgical evaluation patients epilepsy. We review here evidence detection MEG, emphasis on simultaneous recordings MEG SEEG. In particular, we discuss how simultaneously recording depth surface signals enables investigate correlation between invasive actually recorded structures. also new venues analysis methods reconstructing activities from MEG.